TY - BOOK AU - Castanho,Miguel A.R.B. AU - Santos,Nuno ED - Wiley InterScience (Online service) TI - Peptide drug discovery and development: translational research in academia and industry SN - 9783527636730 AV - RS431.P38 P47 2011 U1 - 615.3 22 PY - 2011/// CY - Weinheim PB - Wiley-VCH KW - Peptide drugs KW - Case studies KW - Drug development KW - MEDICAL KW - Pharmacology KW - bisacsh KW - fast KW - Electronic books KW - local N1 - Includes bibliographical references and index; Front Matter -- The Academia-Market Bouncing of Peptide Drugs : Challenges and Strategies in Translational Research with Peptide Drugs. Peptides as Leads for Drug Discovery / Paul J Edwards, Steven R LaPlante -- Marketing Antimicrobial Peptides: A Critical Academic Point of View / Eduard Bardaj̕ -- Oral Peptide Drug Delivery: Strategies to Overcome Challenges / Josias H Hamman, Jan H Steenekamp -- Rational Design of Amphipathic a-Helical and Cyclic [beta]- Sheet Antimicrobial Peptides: Specificity and Therapeutic Potential / Wendy J Hartsock, Robert S Hodges -- Conotoxin-Based Leads in Drug Design / Muharrem Akcan, David J Craik -- Plant Antimicrobial Peptides: From Basic Structures to Applied Research / Suzana M Ribeiro, Simoni C Dias, Octavio L Franco -- Peptide Drugs' Translational Tales : Peptide Drugs before, Through and after Industry Pipelines. Omiganan Pentahydrochloride: A Novel, Broad-Spectrum Antimicrobial Peptide for Topical Use / Evelina Rubinchik, Dominique Dugourd -- Turning Endogenous Peptides into New Analgesics: The Example of Kyotorphin Derivatives / Marta M B Ribeiro, Isa D Serrano, S̤nia S̀ Santos -- The Development of Romiplostim : A Therapeutic Peptibody Used to Stimulate Platelet Production / Graham Molineux, Ping Wei -- HIV vs. HIV: Turning HIV-Derived Peptides into Drugs / Henri G Franquelim, Pedro M Matos, A Salom̌ Veiga -- Sifuvirtide, A Novel HIV-1 Fusion Inhibitor / Xiaobin Zhang, Hao Wu, Fengshan Wang -- Whither Peptide Drugs? Peptides Shaping the Future of Drug Development. Endogenous Peptides and Their Receptors as Drug Discovery Targets for the Treatment of Metabolic Disease / Mary Ann Pelleymounter, Yuren Wang, Ning Lee -- Translation of Motilin and Ghrelin Receptor Agonists into Drugs for Gastrointestinal Disorders / Gareth J Sanger, John Broad, David H Alpers -- Of Mice and Men: Translational Research on Amylin Agonism / Jonathan D Roth, Christine M Mack, James L Trevaskis, David G Parkes -- Peptides and Polypeptides as Immunomodulators and Their Consequential Therapeutic Effect in Multiple Sclerosis and Other Autoimmune Diseases / Ruth Arnon, Michael Sela, Rina Aharoni -- Development of Antibody Fragments for Therapeutic Applications / Sofia Carte-Real, Frederico Aires da Silva, Joao Gonzalves -- Index UR - http://onlinelibrary.wiley.com/book/10.1002/9783527636730 ER -