01674cam a2200301Ia 4500001001500000003000800015005001700023006001900040007000700059008004100066020003200107040002100139100003600160245010600196250001200302260005400314300002300368504005100391505056700442530003701009538003601046650004501082650002401127650001901151655002801170776001801198856015601216CRC00E70991PDFFlBoTFG20171224123336.0m|||||o||d||||||||cr||||090709s2010    flua    sb    001 0 eng d  a9781420071009 (ebook : PDF)  aFlBoTFGcFlBoTFG1 aMartin, Yvonne Connolly,d1936-10aQuantitative drug designh[electronic resource] :ba critical introduction /cYvonne Connolly Martin.  a2nd ed.  aBoca Raton :bCRC Press/Taylor & Francis,cc2010.  axv, 282 p. :bill.  aIncludes bibliographical references and index.0 aOverview of quantitative drug design -- Noncovalent interactions in biological systems -- Preparation of 3D structures of molecules for 3D QSAR -- Calculating physical properties of molecules -- Biological data -- Form of equations that relate potency and physical properties -- Statistical basis of regression and partial least-squares analysis -- Strategy for the statistical evaluation of a data set of related molecules -- Detailed examples of QSAR calculations on erythromycin esters -- Case studies -- Methods to approach other structure-activity problems.  aAlso available in print edition.  aMode of access: World Wide Web. 0aDrugsxStructure-activity relationships. 0aQSAR (Biochemistry) 0aDrugsxDesign. 7aElectronic books.2lcsh1 z978142007099640uhttp://marc.crcnetbase.com/isbn/9781420071009qapplication/PDFzDistributed by publisher. Purchase or institutional license may be required for access.