01768cam a2200337Ia 4500 CRC00E70991PDF FlBoTFG 20171224123336.0 m|||||o||d|||||||| cr|||| 090709s2010 flua sb 001 0 eng d 9781420071009 (ebook : PDF) FlBoTFG FlBoTFG RM301.42 .M37 2010 615.19 M383 Martin, Yvonne Connolly, 1936- Quantitative drug design [electronic resource] : a critical introduction / Yvonne Connolly Martin. 2nd ed. Boca Raton : CRC Press/Taylor & Francis, c2010. xv, 282 p. : ill. Includes bibliographical references and index. Overview of quantitative drug design -- Noncovalent interactions in biological systems -- Preparation of 3D structures of molecules for 3D QSAR -- Calculating physical properties of molecules -- Biological data -- Form of equations that relate potency and physical properties -- Statistical basis of regression and partial least-squares analysis -- Strategy for the statistical evaluation of a data set of related molecules -- Detailed examples of QSAR calculations on erythromycin esters -- Case studies -- Methods to approach other structure-activity problems. Also available in print edition. Mode of access: World Wide Web. Drugs Structure-activity relationships. QSAR (Biochemistry) Drugs Design. Electronic books. lcsh 9781420070996 http://marc.crcnetbase.com/isbn/9781420071009 application/PDF Distributed by publisher. Purchase or institutional license may be required for access. 14741 14741