01904cam a2200349Ia 4500001001500000003000800015005001700023006001900040007000700059008004100066020003200107040002100139090002300160092001800183100001800201245010300219260005200322300002600374500002900400504006400429505063800493530003701131538003601168650003101204650004801235650003701283655002801320776001801348776001501366856015601381999001701537CAH000C7892PDFFlBoTFG20171224123637.0m|||||o||d||||||||cr||||090319s2010 fluad sb 001 0 eng d a9781420078930 (ebook : PDF) aFlBoTFGcFlBoTFG aRC632.P7bT66 2010 a612.398bT6621 aTompa, Peter.10aStructure and function of intrinscially disordered proteinsh[electronic resource] /cPeter Tompa. aBoca Raton :bChapman & Hall/CRC Press,cc2010. axxvii, 331 p. :bill. a"A Chapman & Hall book." aIncludes bibliographical references (p. 265-312) and index.0 aPrinciples of protein structure and function -- A brief history of protein disorder -- Indirect techniques for recognizing and characterizing protein disorder -- Hydrodynamic techniques -- Spectroscopic techniques for characterizing disorder -- Nuclear magnetic resonance -- Proteomic approaches for the identification of IDPs -- IDPs under conditions approaching in vivo -- Prediction of disorder -- Structure of IDPs -- Biological processes enriched in disorder -- Molecular functions of disordered proteins -- Evolution and prevalence of disorder -- Extension of the structure-function paradigm -- Structural disorder and disease. aAlso available in print edition. aMode of access: World Wide Web. 0aProteinsxPathophysiology. 0aProteinsxStructure-activity relationships. 0aProteinsxMetabolismxDisorders. 7aElectronic books.2lcsh1 z97814200789231 z142007892540uhttp://marc.crcnetbase.com/isbn/9781420078930qapplication/PDFzDistributed by publisher. Purchase or institutional license may be required for access. c15428d15428